Vectors, Constructs, Cell Lines, and Expression Systems

Documentation: Version 20.7

Definitions

  • Vectors are typically plasmids that can inject genetic material into cells. Must have a specific nucleotide sequence.
  • Constructs are Vectors which have been modified to include the genetic material intended for injection into the cell.
  • Cell Lines are types of cells that can be grown in the lab.
  • Expression Systems are cell lines that have been injected with a construct.

Entry Forms

The Biologics registry can capture Vectors, Constructs, Cell Lines, Expression Systems, and their relationships. To add these entities to the registry, use the entry forms available on the create menu for any entity.

For example, when you are viewing the Vectors page, you can select Create > Vector, or click Create > Registry to expand the listing and select another entity type to create.

  • Create > Vector
  • Create > Registry > Construct
  • Create > Registry > Cell Line
  • Create > Registry > Expression System
The default fields for each entity type are shown below. Note that the default fields can be changed by administrators to fit your laboratory workflows, requirements, and terminology. For details see Biologics Admin: Grids, Detail Pages, and Entry Forms.

Entity TypeDefault Fields
VectorDescription
Alias
Sequence
Selection Methods
Vector Parents
ConstructDescription
Alias
Vector
Cloning Site
Complete Sequence
Insert Sequences
Construct Parents
Cell LinesDescription
Alias
Expression System
Stable
Clonal
Organisms
Cell Line Parents
Expression SystemsDescription
Alias
Host Cell Line
Constructs
Expression System Parents

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