LabKey Biologics represents materials in various phases of bioprocessing using Samples. Samples of many different types can be defined to represent your development process. They can be standalone compounds, they can have parentage/lineage, they can be aliquoted, used to derive new samples, or pooled. The lineage of samples you track may be both concretely real (such as a parent material or vial) and virtual (such as a Recipe and/or an Expression System used).

Sample Types define the fields and properties for the different kinds of samples in your system.

Sample Types Dashboard

In the LabKey Biologics application, the Sample Types dashboard displays an overview of all the samples known to the system.

Sample Types can be created and edited either inside or outside of the Biologics Application.

Click the name of a Sample Type to see details about the type, including how new names will be generated, plus a grid of the SampleIDs registered of this type. Menus are provided for:

  • Create: Presents the list of what you can create from here, including new Samples of any existing type.
  • Manage Samples: Actions available here include importing samples from file, deleting, and editing in grid or bulk.
  • Jobs: Start a workflow job. If any samples are selected, you can also add them to a new or existing job.
  • Charts: If charts are defined for this kind of sample, you can open them from here.
  • Paging controls.
  • : Download
  • Grid Views: Select from any custom grid views offered for this kind of sample.
  • Sample/Aliquot Selector: Choose from:
    • All Samples (Samples and Aliquots)
    • Samples Only
    • Aliquots Only
Below the menus, the omnibox offers searching, sorting, and filtering like other grids in the system.

Sample Details

Click an individual Sample Id to see its details. A sample details page shows five tabs:

  • Overview: Summary of sample and parent information.
  • Lineage: Shows the parents and children of the current sample.
  • Aliquots: Shows all aliquots created from this sample (if any).
  • Assays: Displays any assay data associated with this sample.
  • Jobs: Shows all jobs involving this sample.
A brief summary of each is shown below. More details are available in the Sample Manager documentation.

Overview

The overview tab shows the values of all properties for the sample.

Use the menu to:

  • Create Samples (of any Sample Type): Only creation of derivatives is supported here. By default this sample will be a parent of the new one(s).
  • Create Workflow Job: By default this sample will be automatically assigned to the job.
  • Upload Assay Data (for any Assay)
  • Delete Sample: Available only when samples do not have dependents like derived samples, assay data, or status that prevents deletion.

Parent Details

Below the panel of details about this sample, you will see a panel of Parent Details giving the type and property values for the parent from which this sample was created. Shown above, "ER-005", one of the expression runs.

Users with appropriate permissions can edit the parent details here when appropriate, changing parents, adding additional "parents" of other types, etc.

Lineage

Sample lineage is available as a graphical view by default, as shown below. Hover over any node for more information, click any node to see details. Click Go To Lineage Grid to see the same information as a grid. Learn more in the topic: Entity Lineage.

Aliquots

A grid of all the aliquots created from this sample. Learn more about creating aliquots in the Sample Manager documentation.

The Aliquot Naming Pattern is part of the sample type definition. The default is the parent sample name (AliquotedFrom) followed by a dash and incrementing counter:

${${AliquotedFrom}-:withCounter}

If instead you wanted to use a dot between the sample name and aliquot number, you'd use the pattern:

${${AliquotedFrom}.:withCounter}

Learn more about customizing aliquot naming patterns here: Aliquot Naming Patterns

Assays

On the Assays tab, you can see all the assay data available for that sample, as well as for all aliquots (and subaliquots) created from it. Click the assay name to see all results for that assay for the sample you are viewing. Select whether grids include data for samples, aliquots of those samples, or both.

Jobs

A grid of links to all the jobs that involve this sample, if any. Click Start a New Job to create a new one with this sample as an input.

Sample Status

The status of samples can be tracked using customizable Sample Status values. There are three main types of status:

  • Available: Can be used.
  • Consumed: Used up, and can longer can be aliquoted or checked out, but remains in the system for analysis and tracking.
  • Locked: Not currently available, but may later become available.

Use Status Settings

Users can assign statuses to their samples throughout the system:

  • At sample creation
  • During file import of new or updated samples
  • When updating a single sample's details
  • In a bulk sample update
Aliquots can have status values separate from their parent sample.

Manage Status Options

From the main menu, click Sample Types then click Manage Sample Statuses. Scroll down to find the current status settings defined.

Learn more in the Sample Manager companion topic for this feature.

Related Topics

LabKey Server Documentation about Samples

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