Hi, and thanks for reaching out.

You may run up against database limits (on number of columns or overall capacity) but there isn't an intrinsic limit on list size in LabKey. We have users successfully using lists with millions of rows. Depending on the reporting and querying you plan to do, of course you may run into performance issues, but that would be true of any large set of data. Lists are a flexible option for representing data that may meet your needs.

Hope that helps,

--Molly